Profile Project

Information updated to: 31/08/2016

Project

Verso la medicina personalizzata: nuovi sistemi molecolari per la diagnosi e la terapia di patologie oncologiche ad alto impatto sociale

Code PON01_02388
Field/s Health and wellbeing
Description The proposed project is based on the confluence of scientific interests between companies and public research centers for the development of new molecular systems for the diagnosis and therapy of socially important oncological pathologies. The novelty of the present project resides in the multidisciplinary approach by which the whole research iter will be developed starting from the choice of specific molecular markers in some tumors and the synthesis of molecular systems able to interact with them up to the preclinical evaluation of obtained compounds. The project will be realized through a strong synergy between public and private centers and complementary technologies that will be made available at all the partners. As part of this project it is also expected to explore new labeling strategies of peptides or proteins by fluorinated prosthetic groups and/or chelating groups for therapeutic and diagnostic applications. Moreover, the project innovation concerns the development of the radiopharmaceutical in a stable formulation. A limit in the development of radiopharmaceuticals is indeed due to the high effect of radiolysis caused by radioactivity that destroys the carrier molecule of radioisotope in a few hours. The radiolytic effect makes the marketing of these radiolabelled molecules impossible. The study of a formulation that stabilizes the final product, even if just for three days, makes the radiolabelled product available for market use. In the present project a new molecular system based on miRNA for the diagnosis on serum of oncological deseases will be also developed. In conclusion, all project activities have the potentiality to lead to products of interest in the clinical field.
Total cost 4,393,430.00 euro
Public contribution
Total public contribution
3,587,237.80 euro

NOP R&C contribution
2,709,911.80 euro

PAC contribution
0.00 euro

Contribution from other funds
877,326.00 euro
Distribution Advancement of distribution in %
Total amount distributed
2,409,098.75 euro

NOP R&C distributed amount
2,166,162.50 euro

PAC distributed amount
0.00 euro

Amount distributed with other funds
242,936.25 euro

Legend

Field/s – Indicates the field or fields in which the project has the most relevance. A project may have more than one field. For some projects it is not assigned. The field are the following 8: "Health and wellbeing", "Food", "Energy", "Environment and Ecology", "Transport and Logistics", "Cultural goods and activities", "Social Innovation" and "Smart Cities".

Description – Descriptive summary of project.

Total cost – Total cost of project.

Public contribution – Three elements are reported:

  • Total commitment – total amount admitted to financing, may include more than contribution to be valued on NOP R&C, also on other funds.
  • NOP R&C admitted contribution
  • PAC admitted contribution
  • Contribution with other funds

Distribution – The following elements are reported:

  • Total distributed amount – takes into account the distributed amount considering both NOP R&C distribution and other funds if provided for
  • NOP R&C distributed amount – amount distributed to financing of project to be valued on NOP R&C
  • PAC distributed amount – amount distributed to financing of project to be valued on PAC
  • Amount distributed with other funds – amount distributed to financing of project with other funds

The distributions refer to the date of last update indicated at top.

Type of beneficiary Public commitment for beneficiary
Research Organisation 1
Large business 1
Public research organisation 1
Medium business 1
Total Beneficiaries 4

Diagnostica e Farmaceutica Molecolari società consortile a responsabilità limitata

Tax File Number: 05905391214
Unique Project Code: B81H11000940005
Location of financial commitments: Campania
Type: Research Organisation

Presentation date 09/04/2010
Approval date 23/10/2015
Start of activity Expected date
01/01/2011
Effective date
01/01/2011
End of activity Expected date
31/12/2015
Effective date
-
Total cost 955,000.00 euro
Public contribution Total
811,750.00 euro
Eligible of NOP R&C
811,750.00 euro
Distribution Total
811,750.00 euro
Amount of NOP R&C
811,750.00 euro

Date of last distribution of NOP R&C
-

BIORICERCHE 2010 SCARL

Tax File Number: 06079121213
Unique Project Code: B61H11001090005
Location of financial commitments: Campania
Type: Large business

Presentation date 09/04/2010
Approval date 23/10/2015
Start of activity Expected date
01/01/2014
Effective date
01/01/2011
End of activity Expected date
31/12/2015
Effective date
-
Total cost 549,103.00 euro
Public contribution Total
428,661.80 euro
Eligible of NOP R&C
428,661.80 euro
Distribution Total
-
Amount of NOP R&C
-

Date of last distribution of NOP R&C
-

CNR - Consiglio nazionale delle ricerche

Tax File Number: 80054330586
Unique Project Code: B51H11000780005
Location of financial commitments: Campania, Extra convergenza
Type: Public research organisation

Presentation date 09/04/2010
Approval date 23/10/2015
Start of activity Expected date
01/01/2011
Effective date
01/01/2011
End of activity Expected date
31/12/2015
Effective date
-
Total cost 1,953,500.00 euro
Public contribution Total
1,660,475.00 euro
Eligible of NOP R&C
1,085,875.00 euro
Distribution Total
1,258,255.00 euro
Amount of NOP R&C
1,085,875.00 euro

Date of last distribution of NOP R&C
-

ADVANCED ACCELERATOR APPLICATIONS (ITALY) S.R.L

Tax File Number: 01493500704
Unique Project Code: B31H11000560005
Location of financial commitments: Campania, Extra convergenza
Type: Medium business

Presentation date 09/04/2010
Approval date 23/10/2015
Start of activity Expected date
01/01/2011
Effective date
01/01/2011
End of activity Expected date
31/12/2015
Effective date
-
Total cost 935,827.00 euro
Public contribution Total
686,351.00 euro
Eligible of NOP R&C
383,625.00 euro
Distribution Total
339,093.75 euro
Amount of NOP R&C
268,537.50 euro

Date of last distribution of NOP R&C
-
Axis - Operational objective I - Scientific and technological fields, generators of industry transformation processes and creators of new sectors (Go to )
Action Strategic scientific and technological areas
Action line Industrial Research (Go to)
Instrument of implementation Invitation to presentation of Industrial Research projects (DD 1/Ric 18/01/10)
NSF - objective Strengthen and evaluate the whole chain of research and cooperation networks between the research system and businesses, to contribute to competitiveness and economic growth; sustain maximum distribution and use of new technologies and advanced services; heighten level of scientific and technical knowledge and skills in the production system and in institutions
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