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Information updated to: 31/08/2016

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Project

PIATTAFORME TECNOLOGICHE INNOVATIVE PER L’INGEGNERIA TISSUTALE

Code PON01_00829

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Description
Beneficiaries
Objectives

Results

Field/s	Health and wellbeing
Description	The project is fitting the purpose of designing and accomplishing innovative technological platforms based on the development of new biotechnological products, biomaterials, diagnostic procedures and devices to be used in regenerative medicine. The main fields of interest of these innovative products will include: orthopedics, cardiology, degenerative diseases of the central nervous system and endocrine-metabolic syndromes. The development of innovative technological platforms for tissue regeneration, in particular in the field of myocardial ischemia and of osteo-articular alterations, will be based on the study of: i. biomimetic systems (scaffolds) and biomedical devices producing physical stimuli to improve specific tissue repair and/or regeneration; ii) establishment of cell lines to produce tissue-specific cytokines and growth factors; iii) validation of new procedures to isolate, purify and maintain stem cell lines to be utilized in regenerative medicine; iv) validation of protocols based on the synergic activity of stem cells and growth factors for the regeneration of different tissue types; v) identification of new molecular targets for a combined treatment of osteoporosis; vi) validation of new diagnostic tests to detect early phases of the disease and to monitor the efficacy of the therapy. The Research Organizations included in the project will develop autonomous research lines that will be coordinated with those performed by the Industries; the fulfillment of the main objectives of the project will improve the technological knowledge of the Research Organizations and their competitiveness in the field of health, biomaterials, biotechnology and tissue ingeneering both at the national and international level. In this way they become qualified as a center of excellence that give life to a network assembling at Distretti Tecnologici. In this project are present numerous industries known in Italy and internationally that operate in the pharmaceutical, biomedical, and biomaterial sectors. These companies routinely perform activity in research and development in the areas they operate. All the activities of research proposed in the project are oriented to the acquisition of knowledge for the realization of novel drugs, industrial processing, preclinical models and diagnostic systems in the sector of regenerative medicine.
Total cost	9,203,102.00 euro
Public contribution		Total public contribution 7,054,460.84 euro NOP R&C contribution 5,356,629.99 euro PAC contribution 0.00 euro Contribution from other funds 1,697,830.85 euro
Distribution	Advancement of distribution in %	Total amount distributed 3,683,473.89 euro NOP R&C distributed amount 3,273,821.13 euro PAC distributed amount 0.00 euro Amount distributed with other funds 409,652.76 euro

Legend

Field/s – Indicates the field or fields in which the project has the most relevance. A project may have more than one field. For some projects it is not assigned. The field are the following 8: "Health and wellbeing", "Food", "Energy", "Environment and Ecology", "Transport and Logistics", "Cultural goods and activities", "Social Innovation" and "Smart Cities".

Description – Descriptive summary of project.

Total cost – Total cost of project.

Public contribution – Three elements are reported:

Total commitment – total amount admitted to financing, may include more than contribution to be valued on NOP R&C, also on other funds.
NOP R&C admitted contribution
PAC admitted contribution
Contribution with other funds

Distribution – The following elements are reported:

Total distributed amount – takes into account the distributed amount considering both NOP R&C distribution and other funds if provided for
NOP R&C distributed amount – amount distributed to financing of project to be valued on NOP R&C
PAC distributed amount – amount distributed to financing of project to be valued on PAC
Amount distributed with other funds – amount distributed to financing of project with other funds

The distributions refer to the date of last update indicated at top.

Type of beneficiary

Public commitment for beneficiary

Micro business	2
University	1
Small business	2
Research Organisation	1
Total Beneficiaries	6

IOM Ricerca

Tax File Number: 04118510876
Unique Project Code: B81C11000970005
Location of financial commitments: Sicilia

Type: Micro business

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Presentation date	09/04/2010
Approval date	01/07/2015
Start of activity	Expected date 01/10/2011	Effective date 01/10/2011
End of activity	Expected date 31/10/2015	Effective date -
Total cost	1,387,215.00 euro
Public contribution	Total 962,596.25 euro	Eligible of NOP R&C 962,596.25 euro
Distribution	Total 673,817.38 euro	Amount of NOP R&C 673,817.38 euro Date of last distribution of NOP R&C -

Università degli studi di Palermo

Tax File Number: 80023730825
Unique Project Code: B71C11000300005
Location of financial commitments: Sicilia

Type: University

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Presentation date	09/04/2010
Approval date	01/07/2015
Start of activity	Expected date 01/10/2011	Effective date 01/10/2011
End of activity	Expected date 31/10/2015	Effective date -
Total cost	537,825.00 euro
Public contribution	Total 457,151.25 euro	Eligible of NOP R&C 457,151.25 euro
Distribution	Total 457,151.25 euro	Amount of NOP R&C 457,151.25 euro Date of last distribution of NOP R&C -

CONSORZIO PITECNOBIO

Tax File Number: 04618840872
Unique Project Code: B61C11002090005
Location of financial commitments: Non disponibile

Type: Micro business

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Presentation date	09/04/2010
Approval date	01/07/2015
Start of activity	Expected date 01/10/2011	Effective date 01/10/2011
End of activity	Expected date 31/10/2015	Effective date -
Total cost	5,053,237.00 euro
Public contribution	Total 3,850,999.59 euro	Eligible of NOP R&C 2,641,699.99 euro
Distribution	Total 1,375,655.88 euro	Amount of NOP R&C 1,102,170.00 euro Date of last distribution of NOP R&C -

IGEA

Tax File Number: 01021130362
Unique Project Code: B31C11000760005
Location of financial commitments: Campania, Extra convergenza

Type: Small business

See beneficiary profile >

Presentation date	09/04/2010
Approval date	01/07/2015
Start of activity	Expected date 01/10/2011	Effective date 01/10/2011
End of activity	Expected date 31/10/2015	Effective date -
Total cost	420,125.00 euro
Public contribution	Total 286,718.75 euro	Eligible of NOP R&C 132,500.00 euro
Distribution	Total 200,773.13 euro	Amount of NOP R&C 132,500.00 euro Date of last distribution of NOP R&C -

Medestea Research & Production

Tax File Number: 08293430016
Unique Project Code: B21C11000750005
Location of financial commitments: Puglia, Extra convergenza

Type: Small business

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Presentation date	09/04/2010
Approval date	01/07/2015
Start of activity	Expected date 01/10/2011	Effective date 01/10/2011
End of activity	Expected date 31/10/2015	Effective date -
Total cost	470,000.00 euro
Public contribution	Total 362,500.00 euro	Eligible of NOP R&C 254,500.00 euro
Distribution	Total -	Amount of NOP R&C - Date of last distribution of NOP R&C -

ISTITUTO ORTOPEDICO RIZZOLI (IRCCS)

Tax File Number: 00302030374
Unique Project Code: B11C11000180005
Location of financial commitments: Sicilia, Extra convergenza

Type: Research Organisation

See beneficiary profile >

Presentation date	09/04/2010
Approval date	01/07/2015
Start of activity	Expected date 01/10/2011	Effective date 01/10/2011
End of activity	Expected date 31/10/2015	Effective date -
Total cost	1,334,700.00 euro
Public contribution	Total 1,134,495.00 euro	Eligible of NOP R&C 908,182.50 euro
Distribution	Total 976,076.25 euro	Amount of NOP R&C 908,182.50 euro Date of last distribution of NOP R&C -

Axis - Operational objective	I - Scientific and technological fields, generators of industry transformation processes and creators of new sectors (Go to )
Action	Strategic scientific and technological areas
Action line	Industrial Research (Go to)
Instrument of implementation	Invitation to presentation of Industrial Research projects (DD 1/Ric 18/01/10)
NSF - objective	Strengthen and evaluate the whole chain of research and cooperation networks between the research system and businesses, to contribute to competitiveness and economic growth; sustain maximum distribution and use of new technologies and advanced services; heighten level of scientific and technical knowledge and skills in the production system and in institutions